Glutamine: An Obligatory Parenteral Nutrition Substrate in Critical Care Therapy

Glutamine: An Obligatory Parenteral Nutrition Substrate in Critical Care Therapy

Critical illness is characterized by glutamine depletion owing to increased metabolic demand. Glutamine is essential to maintain intestinal integrity and function, sustain immunologic response, and maintain antioxidative balance. Insufficient endogenous availability of glutamine may impair outcome in critically ill patients. Consequently, glutamine has been considered to be a conditionally esse...

A.S.P.E.N. position paper: parenteral nutrition glutamine supplementation.

Development and current use of parenteral nutrition in critical care – an opinion paper

Critically ill patients depend on artificial nutrition for the maintenance of their metabolic functions and lean body mass, as well as for limiting underfeeding-related complications. Current guidelines recommend enteral nutrition (EN), possibly within the first 48 hours, as the best way to provide the nutrients and prevent infections. EN may be difficult to realize or may be contraindicated in...

The use of parenteral nutrition in an acute care hospital.

INTRODUCTION Parenteral nutrition (PN) is an important supportive therapy. However, it is expensive and associated with significant complications. Our aim is to describe the patients given PN in 2006, to compare with the 2001 cohort and determine if PN had been prescribed for the appropriate indications. MATERIALS AND METHODS A retrospective cohort study of adult patients receiving PN between...

Parenteral nutrition in adult intensive care.

A healthy person deprived of food will starve to death in approximately 2 months; severe trauma or major surgery reduce that time to about one month. A loss of more than about 12% of total body nitrogen or ofmore than 33% ofbody weight is generally fatal. Lesser degrees of protein/calorie malnutrition, via respiratory muscle weakness, reduced hypoxic drive and decreased tissue oxygenation, cont...